Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats.  |  Epub 2015 Jan 19. The antibacterial activities of Thymus vulgaris essential oil and methanol extract could be associated to the presence of phenolic compounds like carvacrol, thymol, -terpinene and p-cymene, which are all reported to have antibacterial … HHS All essential oil samples were demonstrated to be highly effective against Gram-positive strains, whereas the impact on Gram-negative microorganisms was significantly smaller, but still considerable. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Pseudomonas aeruginosa is a notoriously difficult pathogen to control with antibiotics and disinfectants. Essential Oil Characterization of Thymus vulgaris from Various Geographical Locations. Marchese A, Orhan IE, Daglia M, Barbieri R, Di Lorenzo A, Nabavi SF, Gortzi O, Izadi M, Nabavi SM. 2016 Fall;15(4):861-866. Wiese N, Fischer J, Heidler J, Lewkowski O, Degenhardt J, Erler S. Sci Rep. 2018 Oct 2;8(1):14634. doi: 10.1038/s41598-018-32849-6. The essential oils of four chemotypes of Thymus vulgaris L. (Lamiaceae) were analyzed for their composition and antibacterial activity to assess their different properties. Moreover, TEO and thymol affect the biofilm formation and limit the bacterial swimming and swarming motilities. Plants belonging to the genus Thymus as antibacterial agents: from farm to pharmacy. The essential oil composition of Thymus vulgaris L. and Rosmarinus officinalis L. endemic to France were determined by GC and GC-MS. Oils were assessed for their cytotoxic, antioxidant and antimicrobial activity. Thymus vulgaris L. essential oil (TEO) and thymol are useful for replacing synthetic bacteriostatic agents due to their broad-spectrum bactericidal properties. 2020 Jun 4;10(6):860. doi: 10.3390/biom10060860. J Med Food. This herb is a member of the mint family, and it’s used for cooking, mouthwashes, potpourri and aromatherapy. https://doi.org/10.1016/j.lwt.2020.110354. Epub 2016 Apr 26. Furthermore, antibacterial activity was investigated against several strains of two Gram-positive (Brochothrix thermosphacta and Staphylococcus aureus) and four Gram-negative food-borne bacteria (Escherichia coli, Salmonella abony, Pseudomonas aeruginosa and P. fragi). Thymol intercalated genomic DNA to impact the normal cellular function. COVID-19 is an emerging, rapidly evolving situation. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Iran J Pharm Res. The results obtained indicate that, despite their different properties, the essential oils of selected T. vulgaris chemotypes are potent antimicrobials to be employed as useful additives in food products as well as for therapeutic applications. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. © 2020 Elsevier Ltd. All rights reserved. We use cookies to help provide and enhance our service and tailor content and ads. GC-MS and GC-FID analyses revealed that the essentials oils can be classified into the chemotypes thymol (41.0% thymol), geraniol (26.4% geraniol), linalool (72.5% linalool) and 4-thujanol/terpinen-4-ol (42.2% cis- and 7.3% trans … In general, Thymus vulgaris essential oil showed strong antibacterial activity against B. cereus. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 31 and 37 different compounds were identified representing 99.64% and 99.38% of the thyme and rosemary oils respectively, where oxygenated monoterpenes constituted the main chemical class. By continuing you agree to the use of cookies. The essential oil composition of Thymus vulgaris L. and Rosmarinus officinalis L. endemic to France were determined by GC and GC-MS. Oils were assessed for their cytotoxic, antioxidant and … Miladinović DL, Ilić BS, Kocić BD, Ćirić VM, Nikolić DM. Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review. Oil of thyme is derived from thyme, also known as Thymus vulgaris. NLM Thymol and Thymus vulgaris L. essential oil disrupted cell membrane. Our study further confirms that the accumulation of intracellular ROS caused by TEO and thymol can result in oxidative stress-mediated DNA damage. Clipboard, Search History, and several other advanced features are temporarily unavailable. Antibacterial and antifungal activities of thymol: A brief review of the literature. Food Chem. TEO and thymol potently combat the planktonic P. aeruginosa and directly change the cell structure. Foods. between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts [24] Thymus vulgaris essential oil: Chemical composition and antimicrobial activity [25] Factors that interact with the antibacterial action of thyme essential oil … It’s … The terpenes of leaves, pollen, and nectar of thyme (Thymus vulgaris) inhibit growth of bee disease-associated microbes. In addition to livening up the flavor of food, the thyme plant (Thymus vulgaris) is also the source of thyme essential oil. Synergistic Antifungal, Allelopatic and Anti-Proliferative Potential of Salvia officinalis L., and Thymus vulgaris L. Essential Oils. This study provides a potential approach for the development and utilization of natural essential oils and bioactive compunds as novel food additives in the food processing. Gram stain, SEM and TEM showed that thyme oil degrades the cell wall and membrane integrity of B. cereus. Get the latest public health information from CDC: https://www.coronavirus.gov. Sharifi-Rad J, Miri A, Hoseini-Alfatemi SM, Sharifi-Rad M, Setzer WN, Hadjiakhoondi A. Satyal P, Murray BL, McFeeters RL, Setzer WN. Pain Res Manag. 2016 Oct 27;5(4):70. doi: 10.3390/foods5040070.  |  USA.gov. GC-MS and GC-FID analyses revealed that the essentials oils can be classified into the chemotypes thymol (41.0% thymol), geraniol (26.4% geraniol), linalool (72.5% linalool) and 4-thujanol/terpinen-4-ol (42.2% cis- and 7.3% trans-sabinene hydrate, 6.5 % terpinen-4-ol). P. aeruginosa cell membrane integrity is destroyed as evidenced by an increase in permeability of the inner and outer membranes and the leakage of intracellular biological macromolecules (DNA). Please enable it to take advantage of the complete set of features!  |  NIH Antibacterial Investigation of Thyme Essential Oil and Its Main Constituents in Combination with Tetracycline. 2018 Jan 16;23(1):185. doi: 10.3390/molecules23010185. Pseudomonas aeruginosa was inactivated after thymol and Thymus vulgaris L. essential oil exposure. Get the latest research from NIH: https://www.nih.gov/coronavirus. Abedi SM, Yarmand F, Motallebnejad M, Seyedmajidi M, Moslemi D, Bijani A, Hosseinimehr SJ. Chemical composition and biological activity of Pulicaria vulgaris essential oil from Iran. Thymol intercalates in the P. aeruginosa genomic DNA to affect the normal function of DNA and even cause bacterial death. eCollection 2018. … Thymol and Thymus vulgaris L. essential oil exhibited antibiofilm formation activity. 2018 May 8;2018:7801543. doi: 10.1155/2018/7801543. Thyme oil comes from the perennial herb known as Thymus vulgaris. 2016 Nov 1;210:402-14. doi: 10.1016/j.foodchem.2016.04.111. This site needs JavaScript to work properly. Food Chem. 2015 Apr 15;173:339-47. doi: 10.1016/j.foodchem.2014.10.042.